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NovaSeq X Series 25B vs Revio SPRQ-Nx

RANKED BY VENDOR-ADVERTISED CONSUMABLE COST PER HUMAN GENOME (USD) #3 VS #4 CHECKED 06 SEPT 2026
Side by side
Verdict

NovaSeq X Series 25B ranks #3 of 4 on Vendor-advertised consumable cost per human genome (USD) ($200 / genome); Revio SPRQ-Nx ranks #4 ($345 / genome).

Rank 03 of 4 · leads
Vendor-advertised consumable cost per human genome (USD)
$200 / genome
MakerIllumina
Date2023
Verified04 Sept 2026
Evidence
Illumina NovaSeq X Series page: "Affordably analyze whole genomes: Expand whole-genome sequencing (WGS) in your lab with the $200 USD genome". Footnote: "$200 USD genome on NovaSeq X Series is delivered at list price on the 25B flow cell (sequencing consumables only), assuming 100 Gb/genome." Library prep, labour and analysis are not in the $200.
Rank 04 of 4
Vendor-advertised consumable cost per human genome (USD)
$345 / genome
MakerPacBio
Date2026
Verified04 Sept 2026
Evidence
PacBio Revio brochure: "Affordability ~$345 human HiFi genome". Footnote: "$345 per human HiFi 20X genome assumes US list price of $690 for sequencing reagents for one Revio acquisition, which has an expected yield of 120 Gb, equivalent to two 20x human genomes." HiFi long-read chemistry, so the product is not interchangeable with the short-read Ultima/Illumina rows; the locked metric is still vendor-advertised consumable $/genome.
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Source Ultima Genomics WGS product page; Illumina NovaSeq X Series applications page; PacBio Revio brochure (SPRQ-Nx list-price footnote) Last checked 06 Sept 2026
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